Polynucleotides Treatment
Polynucleotides Treatment
Polynucleotides Treatment
At Bolton Aesthetics Clinic, these Polynucleotide treatments are performed by Gail herself—a highly qualified practitioner with extensive credentials, including GRMN, DPSN, BSC (Hons) MSc, and nurse prescriber status—ensuring you receive the highest standard of care with optimal safety and results.
About Polynucleotide Treatments
Think of Polynucleotides as sophisticated communicators that speak directly to your skin cells, encouraging them to behave more youthfully. Unlike traditional treatments that simply address visible signs of aging, these remarkable biostimulators work at the source—triggering your skin’s innate regenerative processes to create meaningful, long-lasting improvement. By stimulating fibroblasts (the cells responsible for collagen production), polynucleotides don’t just temporarily mask aging—they actively reverse it at a cellular level.
With Gail’s advanced medical qualifications and specialized training, you can trust that your polynucleotide treatment delivers optimal results. Her comprehensive understanding of skin physiology allows for precise application tailored to your specific concerns, whether you’re seeking preventative care in your 30s or more significant rejuvenation in later years. At Bolton Aesthetics Clinic, we believe in treatments that work with your body’s natural processes to create results that look entirely natural yet remarkably effective.

Treatment Applications
Polynucleotides are remarkably versatile and can address multiple concerns:
Facial Rejuvenation
Dark Circles and Eye Area
Hyperpigmentation and Sun Damage
Scarring and Stretch Marks
Hair Loss Treatment

How Polynucleotide Treatments Work
The Science Behind Skin Regeneration
Polynucleotides (polydeoxyribonucleotides) are long chains of nucleotides that make up DNA and RNA molecules. Derived from fragments of fish DNA that closely resemble human DNA, these molecules function as powerful biostimulators when injected into the skin. Their molecular structure allows them to penetrate deep into tissues, where they:
- Stimulate fibroblast activity, increasing collagen production by up to 47% in just 23 days
- Create a thicker, healthier epidermis with improvements of 52% in 23 days
- Reduce inflammation through potent antioxidant properties
- Enhance cellular metabolism and tissue oxygenation
- Promote hyaluronic acid production for deep hydration
As a nurse prescriber with advanced degrees, Gail brings comprehensive understanding of these complex biochemical processes to each treatment, ensuring the appropriate protocol for your specific skin condition and concerns.
The Treatment Process
Your polynucleotide treatment at Bolton Aesthetics Clinic begins with a thorough consultation where Gail assesses your skin condition and discusses your goals. The actual procedure is straightforward:
- The treatment area is cleansed thoroughly and may be numbed with topical anaesthetic for your comfort
- Using fine needles, Gail precisely injects small amounts of the polynucleotide solution into multiple points across the treatment area
- The solution is distributed evenly to ensure consistent results
- Depending on the area being treated, the procedure typically takes 30-45 minutes
- After treatment, Gail may apply a soothing serum or mask to minimize any redness
Most clients report minimal discomfort during the procedure, describing it as a series of small pinches. The treatment requires no downtime, allowing you to return to normal activities immediately, though some mild redness or swelling may occur for 24-48 hours.

Key Benefits of Polynucleotide Treatments
Polynucleotides offer numerous advantages for skin health and appearance:
Comprehensive Skin Rejuvenation
- Collagen and Elastin Boost: Significant increase in these crucial structural proteins for firmer, more elastic skin
- Enhanced Skin Thickness: Creates a stronger, more resilient epidermis that better resists damage
- Improved Texture: Refines skin surface for a smoother, more uniform complexion
- Reduced Fine Lines: Diminishes early signs of aging through structural improvement rather than temporary filling
Skin Health Optimization
- Deep Hydration: Replenishes moisture from within rather than just surface application
- Anti-inflammatory Action: Calms irritated skin and helps with conditions like rosacea
- Antioxidant Protection: Helps shield skin from environmental damage
- Enhanced Circulation: Improves nutrient delivery and waste removal for healthier skin cells
Versatile Application
- Preventative Treatment: Ideal for younger skin to maintain health and delay aging signs
- Curative Treatment: Effectively addresses existing concerns in mature skin
- Complementary Effect: Enhances and prolongs results from other aesthetic treatments
- Long-lasting Results: Benefits continue developing for months after treatment
Your Polynucleotide Treatment Consultation
Your journey at Bolton Aesthetics Clinic begins with a comprehensive consultation with Gail herself, who brings her extensive medical background (GRMN, DPSN, BSC (hons) MSc) to every patient assessment. During this thorough evaluation, she will:
- Discuss your skin concerns, goals, and desired outcomes
- Examine your skin quality, elasticity, and specific problem areas
- Review your medical history to ensure treatment safety
- Explain how polynucleotides work and what results you can realistically expect
- Create a personalized treatment plan including recommended number of sessions
- Address any questions or concerns you might have
As a nurse prescriber with advanced qualifications, Gail offers a level of assessment and care that comes from years of medical training combined with specialized aesthetic expertise.
Treatment Protocol and Results
For optimal results, polynucleotide treatments are typically performed as a series:
- Initial Course: Usually 3 treatments spaced 2-4 weeks apart
- Visible Improvement: Many clients notice enhanced skin quality after the first session, with results continuing to improve throughout the treatment course
- Progressive Enhancement: As collagen production increases, improvements continue developing for up to 6 months after completing the treatment series
- Long-lasting Results: Benefits typically last 6-12 months depending on your skin condition and age
- Maintenance Plan: After the initial series, maintenance treatments every 6-9 months help sustain and enhance results

Frequently Asked Questions
How long do polynucleotide treatments last?
Are polynucleotides better than Botox?
What is better, Profhilo or polynucleotides?
How many polynucleotide treatments do I need?
How painful are polynucleotide treatments?
What are the risks of polynucleotides?
What not to do after polynucleotides?
Contact us for your Booking!
Booking an appointment is super easy! Just fill out the booking form with your name, email, postcode, and select the treatment you’re interested in. Our team will get in touch with you directly.
If you’d like to contact me personally, feel free to send me a direct text, WhatsApp message, or email. 07717 211580 Whatsapp Email Direct