Polynucleotides Treatment

Polynucleotides Treatment are advanced skin biostimulators that work at a cellular level to regenerate and rejuvenate the skin from within.

Polynucleotides Treatment

Polynucleotides Treatment are advanced skin biostimulators that work at a cellular level to regenerate and rejuvenate the skin from within.

Treatment Applications

Polynucleotides are remarkably versatile and can address multiple concerns:

Facial Rejuvenation

Perfect for overall facial revitalization, treating fine lines, wrinkles, and improving skin quality across the face. Particularly effective for delicate areas like around the eyes and mouth where skin thinning occurs.

Dark Circles and Eye Area

Offers an excellent alternative to tear trough fillers by strengthening the delicate under-eye skin and improving circulation to reduce discoloration.

Hyperpigmentation and Sun Damage

Helps normalize melanin production and accelerate skin cell turnover to reduce uneven pigmentation and repair sun-damaged skin.

Scarring and Stretch Marks

Promotes tissue regeneration and improved collagen alignment to minimize the appearance of acne scars, surgical scars, and stretch marks.

Hair Loss Treatment

Stimulates follicle regeneration and improves scalp health when used for alopecia and general hair thinning.

How Polynucleotide Treatments Work

The Science Behind Skin Regeneration

Polynucleotides (polydeoxyribonucleotides) are long chains of nucleotides that make up DNA and RNA molecules. Derived from fragments of fish DNA that closely resemble human DNA, these molecules function as powerful biostimulators when injected into the skin. Their molecular structure allows them to penetrate deep into tissues, where they:

  • Stimulate fibroblast activity, increasing collagen production by up to 47% in just 23 days
  • Create a thicker, healthier epidermis with improvements of 52% in 23 days
  • Reduce inflammation through potent antioxidant properties
  • Enhance cellular metabolism and tissue oxygenation
  • Promote hyaluronic acid production for deep hydration

As a nurse prescriber with advanced degrees, Gail brings comprehensive understanding of these complex biochemical processes to each treatment, ensuring the appropriate protocol for your specific skin condition and concerns.

The Treatment Process

Your polynucleotide treatment at Bolton Aesthetics Clinic begins with a thorough consultation where Gail assesses your skin condition and discusses your goals. The actual procedure is straightforward:

  • The treatment area is cleansed thoroughly and may be numbed with topical anaesthetic for your comfort
  • Using fine needles, Gail precisely injects small amounts of the polynucleotide solution into multiple points across the treatment area
  • The solution is distributed evenly to ensure consistent results
  • Depending on the area being treated, the procedure typically takes 30-45 minutes
  • After treatment, Gail may apply a soothing serum or mask to minimize any redness

Most clients report minimal discomfort during the procedure, describing it as a series of small pinches. The treatment requires no downtime, allowing you to return to normal activities immediately, though some mild redness or swelling may occur for 24-48 hours.

Key Benefits of Polynucleotide Treatments

Polynucleotides offer numerous advantages for skin health and appearance:

Comprehensive Skin Rejuvenation

  • Collagen and Elastin Boost: Significant increase in these crucial structural proteins for firmer, more elastic skin
  • Enhanced Skin Thickness: Creates a stronger, more resilient epidermis that better resists damage
  • Improved Texture: Refines skin surface for a smoother, more uniform complexion
  • Reduced Fine Lines: Diminishes early signs of aging through structural improvement rather than temporary filling

Skin Health Optimization

  • Deep Hydration: Replenishes moisture from within rather than just surface application
  • Anti-inflammatory Action: Calms irritated skin and helps with conditions like rosacea
  • Antioxidant Protection: Helps shield skin from environmental damage
  • Enhanced Circulation: Improves nutrient delivery and waste removal for healthier skin cells

Versatile Application

  • Preventative Treatment: Ideal for younger skin to maintain health and delay aging signs
  • Curative Treatment: Effectively addresses existing concerns in mature skin
  • Complementary Effect: Enhances and prolongs results from other aesthetic treatments
  • Long-lasting Results: Benefits continue developing for months after treatment

Your Polynucleotide Treatment Consultation

Your journey at Bolton Aesthetics Clinic begins with a comprehensive consultation with Gail herself, who brings her extensive medical background (GRMN, DPSN, BSC (hons) MSc) to every patient assessment. During this thorough evaluation, she will:

  • Discuss your skin concerns, goals, and desired outcomes
  • Examine your skin quality, elasticity, and specific problem areas
  • Review your medical history to ensure treatment safety
  • Explain how polynucleotides work and what results you can realistically expect
  • Create a personalized treatment plan including recommended number of sessions
  • Address any questions or concerns you might have

As a nurse prescriber with advanced qualifications, Gail offers a level of assessment and care that comes from years of medical training combined with specialized aesthetic expertise.

Treatment Protocol and Results

For optimal results, polynucleotide treatments are typically performed as a series:

  • Initial Course: Usually 3 treatments spaced 2-4 weeks apart
  • Visible Improvement: Many clients notice enhanced skin quality after the first session, with results continuing to improve throughout the treatment course
  • Progressive Enhancement: As collagen production increases, improvements continue developing for up to 6 months after completing the treatment series
  • Long-lasting Results: Benefits typically last 6-12 months depending on your skin condition and age
  • Maintenance Plan: After the initial series, maintenance treatments every 6-9 months help sustain and enhance results

Frequently Asked Questions

Results typically last 6-12 months, with many clients reporting benefits for up to a year after completing a series of three treatments. The longevity depends on factors including age, skin condition, lifestyle, and maintenance care. Gail will recommend an appropriate maintenance schedule during your consultation.
Polynucleotides and Botox serve different purposes. While Botox relaxes muscles to reduce dynamic wrinkles, polynucleotides improve overall skin quality, thickness, and hydration. Many clients choose both treatments for comprehensive results—Botox for expression lines and polynucleotides for skin rejuvenation. Gail’s medical expertise allows her to recommend the best approach for your specific concerns.
Both are excellent biostimulators with slightly different mechanisms. Profhilo primarily delivers concentrated hyaluronic acid for intense hydration, while polynucleotides offer broader regenerative benefits including collagen stimulation, anti-inflammatory effects, and tissue repair. Polynucleotide effects typically last longer than Profhilo. During your consultation, Gail will assess which option better suits your specific skin needs.
Most clients benefit from an initial series of 3 treatments spaced 2-4 weeks apart, followed by maintenance sessions every 6-9 months. Your specific protocol will depend on your skin condition, concerns, and response to treatment. Gail will create a personalized treatment plan during your consultation.
Most clients report minimal discomfort during treatment, describing it as a series of small pinches. Gail typically applies topical anaesthetic cream before the procedure to ensure your comfort. Her gentle technique and medical expertise minimize discomfort throughout the treatment.
Polynucleotides have an excellent safety profile with minimal side effects, which typically include temporary redness, minor swelling, or bruising at injection sites. These generally resolve within 24-48 hours. As a qualified medical professional, Gail conducts thorough consultations to ensure the treatment is appropriate for you and uses precise techniques to minimize any potential complications.
For 24-48 hours after treatment, avoid intense heat (saunas, hot tubs), strenuous exercise, alcohol consumption, and direct sun exposure. Don’t apply makeup for at least 6 hours post-treatment, and avoid harsh skincare ingredients like retinol for 2-3 days. Gail provides comprehensive aftercare instructions tailored to your specific treatment.

Contact us for your Booking!

Thank you so much for taking an interest in the Polynucleotides Treatment at Bolton Aesthetic Clinic

Booking an appointment is super easy! Just fill out the booking form with your name, email, postcode, and select the treatment you’re interested in. Our team will get in touch with you directly.

If you’d like to contact me personally, feel free to send me a direct text, WhatsApp message, or email. 07717 211580 Whatsapp Email Direct

Booking / Contact Form

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Karen Griffin
When I first had a consultation with Gail I was nervous, but she immediately put me at ease. She is very knowledgeable, and I think the fact that she is a qualified nurse also helped to allay any worries. Gail was informative without being pushy. We had a very thorough consultation before my treatment where she gave me the opportunity to ask as many questions as I needed.
Ann Smith
Had a few treatments from Gail, absolutely amazing each one. Extremely professional, knowledgeable, aesthetically pleasing and I felt very welcome. Il definitely be returning! Highly recommend, thankyou Gail ☺️
Sarah Jones
Exceptional advice & service from Gail. Would highly recommend.